The Stoke and Republic of Ireland footballer praised the support Wilfried Zaha and David McGoldrick have received after being racially abused this week.
“(But) What is the difference?” said the 31-year-old winger.
“I receive and have received more abuse than any other player during my nine years in England.”
The Creggan man has been the victim of online abuse throughout his career.
He also received sectarian taunts from opposition fans over his refusal to wear a poppy during the annual remembrance period every November.
British soldiers shot dead 14 civilian and unarmed protestors in Derry in January 1972 on Bloody Sunday.
In a lengthy Facebook, McClean said the lack of support he had received left a “sour taste” in his mouth.
McClean described the racist abuse directed at his fellow Republic of Ireland player, Sheffield United striker McGoldrick and Crystal Palace striker Zaha as “horrendous” and something “nobody should be subjected to”.
“Twelve-year-old boys get arrested for posting racial abuse online to Zaha, again rightly so, has anyone ever been held accountable for mine? No.
“Have I ever had my abuse condemned by the media? No! In fact, quite the opposite.
“The slightest thing that I do that might cause offence to anyone is highlighted by them.”
James also took aim at his Republic of Ireland team-mates, asking if the discrimination he suffered was different to other racist abuse.
“I have seen some of my fellow Irish team-mates post a black square in support of anti-racism as well as post(s) condemning the discrimination, and again rightly so!
“Have I ever seen any of them ever post a public condemnation of the discrimination I get, which funnily enough is a discrimination against them also? That would be a no!
“Does one kind of discrimination hold a higher bearing over another act of discrimination?”
When asked for a reaction to McClean’s Facebook post, a Stoke City spokesman said it had “no comment at this stage”.
Back in January, McClean praised the football authorities and Staffordshire police for their responses at that time to sectarian abuse that he had received over the previous months.