The campaign by the fast-food giant advertises a new Halloween-themed dessert which is called “Sundae Bloody Sundae”.
Thirteen people were killed and 15 people were wounded after members of the Army’s Parachute Regiment opened fire on civil rights demonstrators in the Bogside on Sunday January 30, 1972.
A 14th person later died of their injuries.
Soldier F, a former member of the British Army’s notorious Parachute Regiment, has been accused of murder and attempted murder on one of the worst days of the Troubles.
His case will be back at Derry courthouse on Wednesday, December 4.
A picture of the advertisement circulated widely on social media has caused outrage.
Nial Finegan said the advertisement was “totally unacceptable”, while Rodrigo Rivera advised the chain to give some history lessons to their marketing department.
Another user said “ignorance is the new cool” for McDonald’s in Portugal.
“Shame on you,” he said.
McDonald’s has not yet commented on the story.